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Badly healing wounds, the peri-anal fistula

Badly healing wounds, the peri-anal fistula |


A pioneering study was carried out in collaboration with the IJsselland Hospital in Rotterdam into the effect of PRS on the possible repair of a returning fistula. These poorly healing wounds around the anus opening create a major problem that is still taboo. After all, the classic operations only yielded a 55% cure.

During the classical fistula excision, PRP was also made from blood and SVF from subcutaneous tissue at the same time.

peri-anal fistula_02 |



PRS with SVF was made by mixing PRP with SVF during removal of the fistula and a mucosa plastic from the mucosa.

The first results were very promising!

peri-anal fistula_03 |

Instead of 55%, of the first 18 patients with a fistula, 89% were completely cured!
When reexamined after 6 months with EM MRI, they were completely healed and only normal skin was visible without 1 trace of scar! See here the research poster presented at a large international conference (in collaboration with Erasmus MC, Rotterdam).

Longer-term studies are, of course, needed (and are currently being conducted) before a final judgment on this new approach can be made.

More information can be obtained from Dr. Eelco de Graaf, General Surgeon, IJsselland Hospital, Rotterdam.

Scientific foundation

Do you want to read more scientific studies?

Over the past 10 years, many peer-reviewed publications, written by our own research teams, have appeared on findings from the lab and clinical practice.

Read more here.